• Filariasis is a group of disorders caused by infection with thread-like nematodes belonging to the family Filariidae. They invade lymphatics, and subcutaneous and deep tissues of humans.
• Lymphatic filariasis caused by Wuchereria bancrofti and Brugia malayi.
Treatment
• "Diethylcarbamazine (DEC) 6 mg/kg in three divided doses for 12-21 days kills microfilariae and adult worms.
• Ivermectin is effective in killing microfilariae, but not the adult worms.
• Doxycycline 200 mg per day for 4 weeks plus ivermectin as a single-dose (200 µg/kg).
• Antihistamines and corticosteroids may be necessary to control allergic phenomena.
• Surgery may be of use in established elephantiasis.
Control
• Mass administration of DEC 6 mg/kg as single-dose along with 400 mg of albendazole once in a year in highly endemic areas
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